Pharma companies have utility equipment (like boiler ,AHU ,chiller ,air compressor etc.) and process equipment's (like granulator, FBP, tablets, syrup making and packing machine etc.) All those machinery need to be well conditioned and well maintained as pharma companies have to go various audit at regular interval from Indian FDA and client country s FDA.
All machine sensors should be measure at regular intervals.This all work is carried out by engineering department. For new company all equipment installation have phases like URS,DQ,FAT,SAT,IQ,OQ,PQ etc which need engineering knowledge in addition to user knowledge (i.e pharma production team).
These engineers get to work when a product has been made in the lab. In the lab a drug product can invented or developed in a small scale like in a test tube or vial size. In order to mass produce this drug you can’t just take everything you did and make it bigger and large. There are very sophisticated issues in this process.
One of the biggest issues is thermal management where in a test tube heat can be managed easily, however in large scales this is not possible. Next major issue is purification and extraction process of the active pharmaceutical ingredient (API). Extracting can be done in a laboratory fairly easily, but the larger the process becomes that harder and the more expensive the process becomes.
Many times the original extraction process cannot be duplicated in large scale. The job a pharmaceutical engineer is to figure out how to make the drug in large manufacturing scale.
A Maintenance Engineer within a pharmaceutical or medical device company will be tasked with routine maintenance of manufacturing equipment as well as helping to troubleshoot when issues arise. Due to the regulation of the industry, they are required to keep detailed and accurate documentation of their work.
Electrical engineer works in service department in a pharmaceutical company. A lot of modern pharmaceutical manufacturing uses a lot of automated or semi-automated processes for the manufacturer, packing and warehouse inventory control. All of these will use fairly to very complex electronic control systems. These all need to be installed, validated and maintained. Electrical engineer have important role. It'll be more useful for an electrical engineer if he/she has knowledge of pharmaceutical equipment & electrical instruments.
Service Engineers are required to design, install, or repair equipment related to different sectors of technology world. Their repair and installation duties may be performed at client's home or in a place of business. These engineers can work both in public and private sector in electronic manufacturing companies. Sometimes these workers are required to train customers on how to use certain type of hardware.
Process engineers are responsible for developing new industrial processes and designing new process plants and equipment or modifying existing ones. The processes that they come up with are used to create products ranging from oil and gas to food and drink.
The executive engineer is the first point of contact for all the engineers and assistant engineers. He or she generally supervises the work of engineers and assistant engineers and guides them whenever necessary.
A pharma industry is basically a process industry. As the number of instruments operated simultaneously is very high in pharma industry it is hard to control them manually. Also different types of chemicals need to be mixed in a particular ratio which are hard to achieve manually when your economy of scale is very high.
So to control instruments and maintain a particular level of quality at a good output quantity automation is required which is generally done by PLC/SCADA system. The measurement and control part is taken care by different sensors and analyzers which give feedback to PLC. PLC then control a set of actuators to control the process. So an instrumentation engineer needs to look after these instruments to ensure that the pharma industry keeps on delivering products without stopping.
Once the product is made and manufactured some one has to review the process and make sure the process went as it was supposed to. Everything must get checked, double checked and approved. Everything will than must be submitted to the federal government and tested to make sure they are acceptable for use. These engineers also make sure the best yield is being made. They also monitor the process throughout the years and improve the process and develop new processes that can be implemented by the process engineers.
Chemical engineer knows the process and the process equipment. These engineers make sure all of these equipment do what they are designed to do in its best and most effective way without product contamination and adulteration. They make sure the entire process and the equipment meet all the world's federal regulation, pharmacopoeias, world health organizations.